All filters
Abstracts
Mechanistic modelling of time-to-positivity and colony-forming unit in tuberculosis patients on high-dose rifampicin to improve understanding of biomarker relation
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Drug effect of clofazimine on persistent mycobacteria explain an unexpected increase of bacterial load in patients
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Stratified dosage regimens from early bactericidal activity studies: an application to pretomanid
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
A PBPK modelling approach to simulate the rifampicin-moxifloxacin drug-drug interaction in TB patients
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
An assay to measure drug tolerance of M. tuberculosis in the caseous center of pulmonary lesions
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Levofloxacin target attainment analysis in MDR-TB patients: time is ripe for proactive TDM
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Population Pharmacokinetics of Linezolid in TB Patients: Dosing Regimens Simulation and Target Attainment Analysis
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
PK-PD of isoniazid given at different doses among patients with MDR-TB with INH resistance mediated by inhA mutations: modeling results from ACTG A5312.
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Can longitudinal PKPD biomarkers be used to forecast treatment outcome instead of M2 conversion? A population pharmacokinetic-pharmacodynamic analysis in drug sensitive pulmonary tuberculosis.
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
The OptiRIF study: pharmacokinetics of high-dose rifampicin in children
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Exposures to first-line drugs in African and Indian children with drug-susceptible tuberculosis using novel fixed-dose-combination tablets at WHO dosing recommendation in the SHINE trial
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Ethionamide population pharmacokinetic model and Monte Carlo Simulation in patients with multidrug-resistant tuberculosis
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Increased bactericidal activity but dose-limiting tolerability at 50 mg/kg rifampicin
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Pharmacogenetics and pharmacokinetics of first-line anti-tuberculosis drugs in the HIRIF trial
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Pharmacokinetics and Early Bactericidal Activity of Meropenem (with Amoxicillin/Clavulanate), With and Without Rifampicin, for Drug-Susceptible TB
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Co-administration of pretomanid with rifampin or rifabutin among patients with pulmonary TB: interim PK results from “Assessing Pretomanid for Tuberculosis” (APT) trial
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Relationship between plasma and intracellular concentrations of bedaquiline and its M2 metabolite in South African patients with drug-resistant TB
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
Evaluating hepatotoxicity of bedaquiline treatment in multi-drug resistant tuberculosis patients
Presented at:
International Workshop on Clinical Pharmacology on HIV, Hepatitis and Other Antiviral Drugs 2019
Abstracts
On-Demand Pre- and Post-Exposure Prophylaxis by Vaginal Inserts Containing TAF and EVG In Macaques
Presented at:
International Workshop on HIV Transmission 2019
Abstracts
Pharmacology of Potential Event-Driven Dosing Regimens for HIV Prevention Among Men Who Have Sex with Men
Presented at:
International Workshop on HIV Transmission 2019
Abstracts
The Distribution of Rectal Mucosal CD4 and CD8 Tissue Resident and Non-Tissue Resident Subsets and their Associations with HIV-1 Infectivity in the Ex Vivo Rectal Explant Challenge Model
Presented at:
International Workshop on HIV Transmission 2019
Abstracts
Preliminary Transcriptome Analysis Reveals Immune Signatures Associated with Support of HIV Replication in Ex Vivo Challenged Rectal Mucosa
Presented at:
International Workshop on HIV Transmission 2019
Abstracts
Ex Vivo Rectal Explant Challenge Model of HIV-1 Transmission Reveals Associations Between Endogenous Inflammatory Cytokine Production and HIV Replication
Presented at:
International Workshop on HIV Transmission 2019
Abstracts
Robust CAB-LA Protection of Macaques From SHIV Infection Despite Concomitant Double or Triple STI Infection and Administration of Depot Medroxyprogesterone Acetate
Presented at:
International Workshop on HIV Transmission 2019