HBVCure New
Meeting category
Date(s)
8 Nov 2023
Program Language
English
Location
Boston, United States
Meeting type
Hybrid Workshop
Organizer

International Workshop on HBV Cure 2023

Related Enduring Materials

Enduring Materials

HBV Cure 2023 focused on the many new treatment options that are becoming available for decreasing the burden of the disease, simplifying treatment, and potentially curing and eradicating HBV infection.

All times are in the Eastern Daylight Time Zone (EDT).

If you need another time zone, this website might be useful to you: https://www.worldtimebuddy.com/ 

Virtual Program Book I HBV Cure 2023
Program of HBV Cure 2023
Opening - 8:30
8:30 AM
Welcome
Adam Gehring, PhD
Toronto Centre for Liver Disease, Canada
Session 1 -
Chairs
Marion Peters, MD
Northwestern University, United States
Raymond Chung, MD, FAASLD
Massachusetts General Hospital / Harvard Medical School, United States
8:40 AM
Durability of Response After DAA Therapies
Fabien Zoulim, MD, PhD
Lyon I University / Hospices Civils de Lyon / INSERM, France
8:55 AM
Expanding CHB Treatment Criteria with Nucs as Prelude of Novel Curative Therapies?
Harry Janssen, MD, PhD
Erasmus MC, University Hospital Rotterdam, the Netherlands / Toronto Centre for Liver Disease, Canada
9:10 AM
Are We Only Able to Suppress HDV or is Cure in Reach?
Pietro Lampertico, MD, PhD
University of Milan, Italy
9:25 AM
Discussion
10:00 AM
Coffee Break
Session 2 -
Chairs
Fabien Zoulim, MD, PhD
Lyon I University / Hospices Civils de Lyon / INSERM, France
Marc G. Ghany, MD, MHSc
Liver Diseases Branch, NIDDK, NIH, United States
10:30 AM
Latest Updates on Novel Biomarkers in HBV Cure
Man-Fung Yuen, MBBS, MD, PhD, DSc
University of Hong Kong, Hong Kong
10:45 AM
Next Generation CAMs, New Life for Small Molecules?
Mark Sulkowski, MD
Johns Hopkins University, United States
11:00 AM
Balance of Response and Adverse Events in Immunotherapy for CHB
Jordan Feld, MD, MPH
Toronto Centre for Liver Disease, Canada
11:15 AM
Discussion
12:00 PM
Lunch
Session 3: Clinical Immunology and Immunotherapy Updates -
Chairs
Chloe Thio, MD
Johns Hopkins University School of Medicine/Johns Hopkins University, United States
Georg Lauer, PhD, MD
Massachusetts General Hospital/ Harvard Medical School, United States
13:00 PM
Immunological Profiles Induced by New Therapeutic Vaccines
Eleanor Barnes, PhD, FRCP, F. Med. Sci.
University of Oxford, United Kingdom
13:15 PM
Efficacy and Safety of Targeting PD-L1 with Monoclonal Antibodies
Jinzi J. Wu, Ph.D.
Ascletis Pharma Inc, Hong Kong
13:25 PM
Efficacy and Safety of Targeting PD-L1 in the Liver with ASO Therapy
13:35 PM
Value of Adding Recombinant Antigens to Viral Vector Vaccines
Ventzi Vassilev, PhD
GSK Vaccines, Belgium
13:45 PM
ImmTavs - Safety for Bi-specific T cell Receptors in CHB Patients
Lucy Dorrell, MBBS, MD, FRCP
Immunocore / Oxford University, United Kingdom
13:55 PM
Anti-HBs Monoclonal Antibodes in Nuc-naïve and Combo Therapies
Carey Hwang, MD, PhD
Vir Biotechnology, Inc., United States
14:05 PM
Discussion
14:35 PM
Coffee Break
Session 4: Update on Viral Targets for HBV/HDV Therapy -
Chairs
Raymond Schinazi, PhD, DSc
Emory University Center for AIDS Research (CFAR), United States
Nezam Afdhal MD, DSc
Medicine Harvard Medical School / Beth Israel Deaconess Medical Center (BIDMC), United States
15:05 PM
Discrimination of Integrated vs. cccDNA Derived HBsAg
Chloe Thio, MD
Johns Hopkins University School of Medicine/Johns Hopkins University, United States
15: 20 PM
Does siRNA Restore Host Control and Could it Lead to Sustained HBsAg Suppression?
Michael J. Sofia, Ph.D
Arbutus Biopharma, Inc., United States
15:30 PM
Second Generation CAMs Leading to HBsAg Decline
Matthew McClure, MD
Aligos, United States
15:40 PM
Bepirovirsen in Combination with Peg-IFN and Other Molecules
Stuart Kendrick, MD, PhD, MRCP
GSK / Cambridge University Hospitals, United Kingdom
15:50 PM
Value of Bulevirtide Combination with PEG-IFN in HDV
Dmitry Manuilov, MD
Gilead Sciences, Germany
16:00 PM
Debate/Discussion of Drug Progress
Session 5: Panel Discussion -
Chairs
Harry Janssen, MD, PhD
Erasmus MC, University Hospital Rotterdam, the Netherlands / Toronto Centre for Liver Disease, Canada
Adam Gehring, PhD
Toronto Centre for Liver Disease, Canada
16:30 PM
Round Table Discussion on Endpoints & Biomarkers: Partial vs. Functional Cure
Marion Peters, MD
Northwestern University, United States
Chloe Thio, MD
Johns Hopkins University School of Medicine/Johns Hopkins University, United States
Pietro Lampertico, MD, PhD
University of Milan, Italy
Marc G. Ghany, MD, MHSc
Liver Diseases Branch, NIDDK, NIH, United States
Jordan Feld, MD, MPH
Toronto Centre for Liver Disease, Canada
Man-Fung Yuen, MBBS, MD, PhD, DSc
University of Hong Kong, Hong Kong
17:05 PM
AASLD Preview
Adam Gehring, PhD
Toronto Centre for Liver Disease, Canada
17:20 PM
Closing Remarks
Harry Janssen, MD, PhD
Erasmus MC, University Hospital Rotterdam, the Netherlands / Toronto Centre for Liver Disease, Canada
17:30 PM
End of the Workshop
Overview
Welcome

HBV Cure 2023 Group Photo


The International Workshop on HBV Cure 2023 took place as a live workshop on 8 November 2023 in Boston, United States.

Since 2014, the International Workshop on HBV Cure has been a scientific platform acting as a catalyst to accelerate the progress for achieving a cure. Around the globe, more than 250 million people live with hepatitis B (HBV). The purpose of the workshop is to inform the participants about the developments in the work to find a cure for HBV. The meeting will be highly interactive with input from experts out of the arena of basic, translational, and clinical HBV research.

The field of HBV treatment is undergoing major changes and is on the verge of a paradigm shift. The many new treatment options that are becoming available provide great hopes for decreasing the burden of the disease, simplifying treatment, and potentially curing and eradicating HBV infection.

In order to optimize curative treatment for HBV, outstanding speakers from around the globe will share the newest therapeutic options for viral hepatitis, and experts will discuss the path forward to cure this deadly disease, leading to liver cirrhosis and liver cancer. Questions on which endpoints to use in therapeutic trials and how to combine different agents targeting the virus and/or immune system will be extensively discussed.

This workshop also brings together global inter-disciplinary experts to provide a framework for how academia and industry should collaborate to achieve the goal of curing hepatitis B.

Program Directors
Harry Janssen 2019
Harry Janssen, MD, PhD
Erasmus MC, University Hospital Rotterdam, the Netherlands / Toronto Centre for Liver Disease, Canada
General Information
  • If you missed the previous edition of the International Workshop on HBV Cure 2022, you can still watch the enduring materials. Presentations and slides are publicly available here.
Venue
The venue of the 10th International Workshop on HBV Cure was:

Boston Park Plaza Hotel 
Address: 50 Park Plaza, Boston, MA 02116, United States
Website: https://www.bostonparkplaza.com/
Networking Dinner
Boston Park Plaza Hotel 
Address: 50 Park Plaza, Boston, MA 02116, United States
Website: https://www.hilton.com/en/hotels/bossrhh-hilton-boston-park-plaza/

This is not included in the registration fee.
Unique Features
- Invited lectures from international experts

- Interactive roundtable discussions

- Ample time for discussion
Who should attend?
- Clinicians
- Researchers
- Academia
- Industry
- Government representatives
Meeting Objectives
The objectives of this workshop were to:

- Discuss how to reach an HBV functional cure with newly developed agents targeting the immune system or the viral replication cycle;
- Develop endpoints and better biomarkers for these studies; and
- Discuss how new agents should be combined to reach the goal of a functional cure.
Learning Objectives
After attending this workshop, participants are able to:

- Critically evaluate biomarkers used in clinical HBV studies;
- Outline advances made to cure HBV; and
- Critically assess current approaches taken to achieve the development of a functional cure.
Code of Conduct
All attendees, speakers, co-organizers, partners, endorsers, suppliers, volunteers, and employees at any of our programs are expected to observe our Code of Conduct. We cannot tolerate any form of discrimination, harassment, disrespect, or the marginalization of those involved in our programs. All participants of VE and AME-organized programs are expected to treat others with dignity and respect at all times.

Any individual who feels discriminated against, harassed, disrespected, or marginalized is encouraged to report the incident(s) to VE and AME via info@amededu.com or to one of our on-site personnel.

Any participant who is found to have exhibited any inappropriate conduct or behavior against others may be removed from the program.
Practical Information
Ethical MedTech
We are glad to inform that the International Workshop on HBV Cure 2023 has received COMPLIANT status from Ethical MedTech Europe platform.

For more information, you can visit the website of Ethical MedTech EU with the following link: https://www.ethicalmedtech.eu/
Certificate of Attedance
A certificate of attendance will be sent to participants that successfully complete the program and post-meeting survey.
Language
The official language of the meeting was English.
Accomodation
Accommodation was not included in the registration fee.
Photographs, Audio, and Visual Recording
Photographs, audio, and video recordings were not permitted at the official workshop sessions. Only the official medical writer appointed by the organization may make recordings. All presentations were posted here as soon as possible after the workshop had finished, provided the speaker has given permission to do so.
Liability and Insurance
By registering for the workshop participants agree that the organizers do not accept responsibility for medical-, travel- or personal insurance. Participants are advised to take out their own insurance policies.
Disclaimer
This workshop is intended for educational purposes only and aims to offer participants the opportunity to share information. The Organizing Secretariat of this event, AME and VE, cannot accept any liability for the scientific content of the sessions or for any claims which may result from the use of information or publications from this meeting. AME and VE disclaim all liability for injuries or losses of whatever nature incurred by individuals attending the workshop.
Registration
Early Fee Deadline: 8 March 2023 at 23:59 EDT
Fees & Conditions

Regular Delegates - In-Person Participation

Regular Delegates
- Virtual Participation 

Industry*

Early Fee (payment before/on 8 March 2023)

€ 295

€ 147,50

€ 1.095

Standard Fee (payment before/on 6 November 2023)

€ 695

€ 347,50

€ 1.495

Same Day Fee (payment on/after 6 November 2023)

€ 895

€ 447,50

€ 1.695

Discounts

Early-career investigators /Regular Delegates from Resource-Limited Settings (RLS)** WITH ACCEPTED ABSTRACT

Complimentary Registration

Early-Career Investigators /Regular Delegates from Resource-Limited Settings (RLS)** WITHOUT ACCEPTED ABSTRACT

50% Off Current Regular Delegate Fee

NGO Representatives / Government Representatives (i.e. MOH, NIH, NIAID, etc.) / Advocates

50% Off Current Regular Delegate Fee

Representatives of sponsoring industry / endorsing organizations ***

Please contact the conference secretariat

* To register on the workshop dates and revisit the recordings of the live stream on the virtual portal.

** Countries included in the low-income and lower middle-income economies of the World Bank Classification.

*** Industry and endorser representatives may receive a discount based on the level of support provided to the event. For more support and registration information, please contact us via Brenda.Evan@amededu.com

If you have financial concerns or are eligible for a discount, please contact the conference secretariat via Daria.bohdanova@amededu.com

IMPORTANT
  • AME (Academic Medical Education) reserves the right to cancel improper registrations. Claims for a refund will not be honoured.

  • We strongly advise that you register early to ensure your registration is secured. 

  • Submission of your online registration does not guarantee that your registration has been accepted. Your registration is final when full prepayment has been received and a confirmation of your registration has been sent.

Registration Fee Includes
- Access to all scientific sessions
- Access to enduring materials
- Virtual workshop materials
- Conference pack, including program book
Group Registration
For registration of groups larger than 5 participants, please contact the Conference Secretariat via Daria.bohdanova@amededu.com
Early-Career Investigators / Academia from Resource-limited Settings (RLS)
We are pleased to offer a 50% discount on the current Academia registration fee for early career investigators and academia from low-income and lower-middle-income countries.

To be eligible as an early-career investigator, one should be:
- a current Master/PhD student; OR
- have obtained an MD/PharmD/PhD degree in the last five years.

An application form (available below) needs to be completed by a supervisor and received by the Conference Secretariat via Daria.bohdanova@amededu.com at least two weeks prior to the start of the workshop. AME and VE will contact the early career investigator with instructions regarding the registration procedure.
Accomodation
Accommodation is not included in the registration fee.
Payment
By credit card only: online or by written authorization.

Please contact the conference secretariat via Daria.bohdanova@amededu.com if you need to make alternative arrangements or have financial concerns.
Cancellation Policy
In case of cancellation, the following refunds are applicable:

- Cancellation before/on 1 October 2023: 50% refund (minus an administration fee of €40)

- Cancellation after 1 October 2023: Unfortunately, no refund will be given

If you are unable to attend the conference, a substitute delegate is always welcome at no extra charge, provided that a letter of authorization from the original participant has been received and the conference secretariat has been notified of the name of the substitute delegate before 15 October 2022. A statement (email/letter) of cancellation must be sent to Daria.bohdanova@amededu.com
Liability and Insurance
By registering for the workshop, participants agree that the organizers do not accept responsibility for medical, travel, or personal insurance. Participants are advised to take out their own insurance policies.
Media Registration
In order to register as a media participant for the workshop, the conference secretariat needs to receive:

1. Proof of accreditation
2. Valid identification (e.g. passport)
3. A letter from your assignment giver stating the details of your assignment (e.g. editor)
4. At least 3 previous written assignments in recognized outlets on HIV. If you are a freelance journalist, the assignments can be from different (recognizable) news outlets. Links to online publications are accepted
5. The website of the publication(s)/blog(s) that will be featuring your story on this workshop

A free or reduced registration fee may apply for accredited media participants depending on availability. Preference will be given to credible print and online news sources. Please contact the conference secretariat for registration conditions.

We would like to receive a copy of your workshop report/ article once it is finalized.
All credentials will be verified by the Organizing Committee of the Workshop. Media representatives are kindly requested to register by sending the above-mentioned information to info@amededu.com.

Important: Media is restricted to the written press. Recording on film or photo is not allowed. Virology Education will request a copy of the written piece once it is finalized. Media representatives must also agree to abide by the 2021 embargo policy.
Disclaimer
This workshop is intended for educational purposes only and aims to offer participants the opportunity to share information. The organizing secretariat of this workshop, AME and VE cannot accept any liability for the scientific content of the sessions or for any claims which may result from the use of information or publications from this workshop. Virology Education disclaims all liability for injuries or losses of whatever nature incurred by individuals attending the workshop. In case of cancellation of the meeting due to unforeseen circumstances, AME and VE cannot be held responsible for expenses made for travel, accommodation, visa applications, etc.
Committees
Program Directors
Harry Janssen 2019
Harry Janssen, MD, PhD
Erasmus MC, University Hospital Rotterdam, the Netherlands / Toronto Centre for Liver Disease, Canada
Organizing Committee

The members of the Organizing Committee are a group of carefully selected experts and inspirational leaders in their respective fields. They meet frequently to discuss the scientific program of the workshop and identify interesting topics and candidate speakers.

Support
Silver Level

Support Our Initiative

Financial backing helps us deliver an impactful meeting experience for the benefit of healthcare professionals, researchers, and community representatives involved in HBV Cure.
 
This collaboration plays a vital role in both the organizational as well as scientific success of the program.
 
To show your commitment to the cause and get in touch with us for a tailored support package, please contact Brenda Evan via Brenda.Evan@amededu.com. 
 
Benefits of Support 
By supporting this program, we can offer the following advantages for your company.* Please contact us for the most recent support level benefits for this program.

  • Symposium opportunities
  • Non-commercial interviews with company representatives
  • Verbal acknowledgment during the program 
  • Discounted and complimentary registrations for your representatives
  • Company acknowledgment on digital meeting materials including but not limited to newsletters, flyers, the streaming platform, and our website
  • Company acknowledgment on printed meeting materials including but not limited to banners and the program book
  • Digital and printed advertising opportunities 
  • Social media shout-outs
  • Logo on the conference bag 

 
*Subject to the support level

Endorsers
Previous Editions
Venue
Venue

The confirmed venue details for the International Workshop on HBV Cure 2023 can be found below.

In case you have any questions or concerns regarding the venue, please feel free to contact us at Daria.Bohdanova@amededu.com

Boston
Media
Group Photo
HBV Cure 2023 Group Photo
Invitation to Join the International Workshop on HBV Cure 2023

Invitation from Harry Janssen, MD, PhD, Erasmus MC, University Hospital Rotterdam, the Netherlands / Toronto Centre for Liver Disease, Canada and Adam Gehring, PhD, Toronto Centre for Liver Disease, Canada.

Language
Ratings previous edition
Overall event experience
5.0
(39)
Content is relevant to my practice
4.8
(39)
Content was presented clearly
4.7
(39)
Content was free from commercial bias
4.7
(39)