International Workshop on HIV & Pediatrics 2019

Day 1 -Friday, 19 July 2019

Official Openining - 08:00

08:00

Opening Words

Lynne Mofenson, MD

Elizabeth Glaser Pediatric AIDS Foundation, United States

Noris Pavía Ruz, MD

Autonomous University of Yucatán State, Mexico

Guillermo Vázquez-Rosales

Pediatric Hospital, Mexico

Session 1: Global Update on Pediatric HIV -

Moderator

Elaine Abrams, MD

Columbia University, United States

Noris Pavía-Ruz

National Autonomous University, Mexico

08:30

2019 Update on the HIV Epidemic in Infants, Children, Adolescents and Women

Mary Mahy, ScD, MHSc

UNAIDS, Switzerland

08:45

What’s New from WHO on Pediatric Antiretroviral Therapy

Martina Penazzato, MD, MSc, PhD

WHO, Switzerland

09:00

Population HIV Impact Assessments - What Can We Learn about Pediatric HIV

Suzue Saito, PhD

ICAP at Columbia University, United States

Session 2: Pediatric Care and Treatment -

Moderator

Pablo Rojo

Hospital 12 de Octubre, Spain

Jorge Pinto, MD, DSc

Federal University of Minas Gerais, Brazil

09:45

Long-acting and Innovative Formulations and Drug Delivery Devices - Possiblities for Children and Adolescents?

Charles Flexner, MD

Johns Hopkins University School of Medicine, United States

10:45

Finding Kids, Treating Kids- Innovations in Case Finding, Treatment and Care

Saeed Ahmed, MD, MSc

Baylor College of Medicine, Malawi

11:15

Oral Abstract Presentations

Community Based Index- and Mobile Testing are Complementary and Effective in Pediatric HIV Case Finding in Tanzania a

Jemma Bisimba, Tanzania

The Cost-Effectiveness of Point-of-Care Platforms for Early Infant Diagnosis of HIV Infection in Southern Province, Zambia

Catherine Sutcliffe, USA

Virological Outcomes and ART Discontinuation in Children Switching to Dolutegravir in The UK/Ireland: A Propensity Score Analysis

Siobhan Crichton, United Kingdom

Tenofovir Alafenamide-Based Regimens: A Pooled Resistance Analysis in Pediatric Participants

Stephanie Cox, USA

Population Pharmacokinetics of Nevirapine in Preterm Infants and Prediction of Doses Needed For Treatment in Combination with other Antiretrovirals

Adrie Bekker, South Africa

Session 3: Comorbidities/Infections -

Moderator

Moherdran Archary, BMedSc (Hon), MPH, PhD

University of KwaZulu Natal, South Africa

Sharon Nachman, MD

SUNY Health Science Center Stony Brook, United States

14:30

Oral Abstract Presentations:

Systemic Inflammation and Structural Brain Changes in Perinatally HIV+ Adolescents

Jacqueline Hoare, South Africa

Associations Between Cholesterol, Apolipoprotein E Genotype Variants, Cognition and Brain Structure in Perinatally HIV+ Adolescents

Jacqueline Hoare, South Africa

Malignancies in Children With HIV Across Eastern and Western Europe and Thailand

Ali Judd, USA

Shorter Telomeres Among HIV+ Cart-Naïve and Cart-Treated Children, and Those Presenting with Abnormal Lung Function

Louis-Marie Yindom, UK

Atazanavir Exposure in Utero and Risk of Multiple Signals of Neurodevelopmental Dysfunction in 5-Year-Old HIV-Exposed Uninfected Children

Tzy-Jyun Yao, USA

Clinical Case Presentations -

Moderator

Rohan Hazra, MD

NIH, USA

Jason Brophy, MD, MSc, DTMH, FRCPC

University of Toronto, Canada

16:15

TB stigma reduction strategies in Asia

Theodore Ruel, PhD

University of California, San Francisco, USA

Jorge Pinto, MD, DSc

School of Medicine, Federal University of Minas Gerais, Brazil

Denis Tindyebwa, MBChB, MMed

African Network for the Care of Children Affected by HIV/AIDS (ANECCA), Uganda

Short Oral Poster Presentations

The Clinical Impact and Cost-Effectiveness of Routine HIV Screening and Testing at Infant Immunization Visits in Côte d’Ivoire (CI), South Africa, and Zimbabwe

Andrea Ciaranello, USA

Safety and Efficacy of E/C/F/TAF In Virologically Suppressed, HIVInfected Children Through 96 Weeks

Natella Rakhmanina, USA

Neurodevelopmental Outcome at 11 Months in Perinatally HIV-Infected Infants: Does Starting Very Early Antiretroviral Therapy Help?

Barbara Laughton, South Africa

T Cell Senescence and Exhaustion In Perinatally HIV Infected Children (PHIC)

Beatriz Thome, Brazil

17:30

Poster Viewing and Welcome Reception

Poster Walk: PMTCT Programs

Leader: Moherndran Archary

HIV Treatment Coverage and Antenatal Care Among Non-Citizen Pregnant Women in Botswana

Rebecca Zash, USA

Too Little, Too Late: Early Lessons on MTCT Risk from HIV Positive Infant Case Investigation in Zimbabwe

Tinashe Chinyanga, Zimbabwe

Challenges with Recognition of Newborns at High Risk for Perinatal HIV Transmission in Rural Western Cape, South Africa

Tracy Cummins, South Africa

Final HIV Outcome for Exposed Infants: Improving Mother-Baby Pair Retention in Prevention of Mother-to-Child Transmission Care in Eswatini Through Proactive Community Follow-Up

Menzi Ginindza, Swaziland

"Effective Community Engagement and Participation, Key to Nigeria Achieving the First 90’ target of eMTCT."

Gideon Sorochi Okorie, Nigeria

Poster Walk: Pediaric Case Finding

Leader: Ali Judd

Creating Demand for HIV Testing Services (HTS) among School-aged Children

Menzi Ginindza, Swaziland

Financial Incentives Increase Pediatric HIV Testing among HIV Positive Caregivers

Anjuli Wagner, Kenya

Untested Children Reached through Index Case Testing Often have Previously Tested Siblings and Poor Historic PMTCT Engagement

Jillian Neary, USA

Perception that a Child is HIV-Positive and Fear that the Child will be Tested are Barriers for Seeking Medical Care for the Child by HIVPositive Caregivers

Cyrus Mugo, Kenya

Concurrent Implementation of Targeted and Blanket Provider-Initiated Testing and Counseling against Symptom-based Diagnostic HIV Testing among Children and Adolescents in Cameroon: A Comparative Effectiveness Study

Habakku Yumo, Cameroon

Poster Walk: Pediatric Antiretroviral Drugs

Leader: Gareth Tudor-Williams

Pharmacokinetics, Safety and Tolerability of Doravirine in Adolescents with HIV-1

Ann Melvin, USA

Effect of Ready-To-Use Therapeutic Food on Efavirenz and Nevirapine Plasma Levels in Malnourished HIV-infected Children in Uganda

Judy Orikiiriza, Ugansa

Abacavir Use in Young Infants in the UK and Ireland National Paediatric HIV Cohort

Siobhan Crichton, United Kingdom

Children and Adolescents in the UK/ Ireland CHIPS Cohort on Integrase Inhibitors: Safety and Effectiveness

Siobhan Crichton United Kingdom

Lack of Influence of Pubertal Stage on Safety and TFV Pharmacokinetics in TAF-based Regimens

Yapei Liu, USA

Poster Walk: Coinfections and Comorbidities

Leader: Sharon Nachman

Maternal Factors for Adherence in Infant Isoniazid Preventive Therapy Provision among HIV-Exposed Uninfected Infants (HEU) in Kenya

Danae Black, USA

Burden of Tuberculosis among Children and Adolescents on Antiretroviral Therapy in Myanmar

Kyaw-Min Htut, Myanmar

Attention Deficit hyperactivity Disorder in Mexican Children and Adolescents with Perinatally Acquired HIV

Dulce María Morales Pérez, Mexico

Low Cytomegalovirus (CMV) Recurrence among HIV-Infected Children and Adolescents on HAART from a Highly CMV-Seropositive Population

Fernanda Sturzbecher, Brazil

Referral Rewards: Impact of Strengthening Integrated HIV/TB and Malnutrition Community-Facility Referrals among Children Under 5 in Rural Zimbabwe

Tinashe Chinyanga, Zimbabwe

Poster Walk: Pediatric Care Programs

Leader: Noris Pavía-Ruz

Adherence to Anti-retroviral Therapy among Children and Adolescents in Myanmar: a mixed-methods study

Kyaw-Min Htut, Myanmar

Pediatric HIV Care at an Ambulatory Health Center in Maputo, Mozambique

Gabriela Zamudio, Mozambique

Virus Load Differentiated Care of HIV-1 Infected Children and Adolescents is Feasible and Effective in Remote Rural Zimbabwe

Tichaona Mapangisana, Zimbabwe

Retention and Viral Suppression of Children and Adolescents in HIV Care, Zimbabwe

Audry Shava, Zimbabwe

Poster Walk: Adolescents: Viral Suppression , Adherence and Retention

Leader: Pat Flynn

Virological Suppression Among HIV Infected Adolescents and Youths Receiving ART in the National Teaching and Referral Hospital in Kenya

James Mburu Kangethe, Kenya

Mental Health and its Association with Metabolic Outcomes in Youth Living with Perinatally Acquired HIV in the Cape Town Adolescent Antiretroviral Cohort (CTAAC).

Jacqueline Hoare, South Africa

Vertically-Infected Adolescents have Poor Viral Suppression Compared to Horizontally-Infected Youth

Kate Wilson, USA

Drug Resistance Among Youth with Confirmed Virologic Failure on First Line and Response to Second Line ART in Harare, Zimbabwe

Vinie Marwa Kouamou, Zimbabwe

Towards Achieving Undetectable Viral Load: Viral Load Outcomes Among Adolescents Living With HIV on ART in the Manzini Region of Eswatini

Anthony Mutiti, Swaziland

Saturday, 20 July 2019

Special Session -

Moderator

Lynne Mofenson, MD

Elizabeth Glaser Pediatric AIDS Foundation, USA

Botswana Birth Surveillance Update

Rebecca Zash, MD

Beth Israel Deaconess Medical Center, Harvard Medical School, United Kingdom

Botswana MOH/CDC Surveillance Study

Mimi Raesima, MD

CDC, Botswana

Special Update on Pediatric HIV in Pakistan

Martina Penazzato, MD, MSc, PhD

WHO, Switzerland

Session 4: Prevention of New Pediatric HIV Infections (and Improving Maternal Health) -

Moderator

Barbara Burmen, MD

University of Cape Town

Guillermo Vázquez-Rosales, MD

Centro Medico Nacional y México City

08:45

Update on Preconception ARVs and Birth Defects

Claire Thorne, BA, MSc, PhD

University College London, United Kingdom

09:15

Oral Abstract Presentations

Periconceptional Antiretroviral Exposure and Central Nervous System (CNS) and Neural Tube Birth Defects – Data from Antiretroviral Pregnancy Registry (APR)

Vani Vannappagari, USA

Effects Of Dolutegravir and Other Integrase Inhibitors on Folate Transport Pathways

Maciej ZamekGliszczynski, USA

HIV Drug Resistance at Mother-To-Child Transmission and Emergence During Breastfeeding

Ceejay Boyce, USA

Lower Birth Weight-for-Age And Length-for-Age Z-Scores In Infants with In Utero HIV and ARV Exposure: A Prospective Study In Cape Town, South Africa

Dorothy Chiwoniso Nyemba, South Africa

Moderator

Denis Tindyebwa, MBChB, MMed

African Network for the Care of Children Affected by HIV/AIDS (ANECCA), Uganda

Amy Slogrove, MB ChB, MMed, PhD,

Stellenbosch University, South Africa

10:45

Addressing sexual and reproductive health needs for adolescent and young women in low and middle income countries

Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD

Desmond Tutu Health Foundation / University of Cape Town (UCT), South Africa

11:15

Short Oral Poster Presentations

Chronic Maternal Depression Symptomatology Predicts Executive Behavioral Problems in HIV Affected Children in Uganda

Itziar Familiar, USA

Age- and Site-Specific Trends in Advanced HIV Disease At Antiretroviral Therapy Initiation Among HIV-Infected Children in Eastern And Southern Africa: 2003-20177

Peter Elyanu, Uganda

Closing the Treatment Gap For Children: Global and Regional Trends in Pediatric Antiretroviral Therapy Coverage, 2010-2017

Joseph Gregory Rosen, Zambia

Outcomes of Children and Adolescents Living With HIV Considered Lost to Follow Up at IeDEA-SA Cohorts in the Western Cape: Linkage to Western Cape Provincial Health Data Centre Records.

Patience Nyakato, South Africa

Session 5: Adolescents and Young Adults -

Moderator

Ali Judd, PhD

London School of Hygiene and Tropical Medicine, United Kingdom

Valériane Leroy, MD

Inserm, Paris, France

13:45

DEBATE: Transition to Adult Care is Bad for the Health of HIV-Positive Youth

Rachel Vreeman, MD, MS

Icahn School of Medicine at Mount Sinai, United States

Hilda Mujuru, MBChB, MMed Paeds, MSc Clin Epi

University of Zimbabwe, Zimbabwe

14:15

Oral abstract presentations

High Uptake and Completion of HIV Self-Testing Using a Novel Community based Delivery System for Young People in Kenya

Kate Wilson, USA

Describing The Characteristics and Long-Term Outcomes of Adolescents Living with Perinatally Acquired HIV in the IeDEASouthern Africa Collaboration: 2004-2017

Priscilla Tsondai, South Africa

Growth and Immunodeficiency of ART-Treated Adolescents Living with Perinatally Acquired HIV: A Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Cohort Collaboration Analysis

Julie Jesson, France

Hospitalization in Perinatally HIV-Infected Adolescents on Antiretroviral Therapy in South Africa: A Prospective Study.

Lisa Frigati, South Africa

The Next Generation: Pregnancy Outcomes in Adolescents and Women Living With Perinatally Acquired HIV in South Africa

Kim Anderson, South Africa