HIVPediatrics
Meeting category
Date(s)
19 Jul 2024 - 20 Jul 2024
Location
Munich, Germany
Meeting type
Hybrid Meeting
CME Credits
12

International Workshop on Pediatrics & HIV 2024

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Enduring Materials

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The presentation videos and slides for speakers’ lectures are made available, provided that they have granted us permission to do so.

Friday, 19 July 2024

Session 1: Global Update on Pediatric HIV -
Global Update on the HIV Epidemic in Infants, Children, Adolescents, and Women
The Epidemiology of HIV and Hepatitis in Pregnant Women, Children, and Adolescents in the European Region
Ali Judd, PhD
University College London / Penta, United Kingdom
Session 2: Pediatric Care and Treatment -
Antiretroviral Drug Resistance in Pediatrics: Extent of the Problem and Management
Natella Rakhmanina, MD, PhD, FAAP, FCP, AAHIVS
Children’s National Hospital, United States
Accomplishments and Challenges of Global Accelerator for Pediatric Formulations
#1 - Emerging Dolutegravir Resistance in Children and Adolescents Living With HIV in Malawi
Katherine Rachel Simon
Malawi
#2 - High Prevalence of Transmitted and Acquired Drug Resistance Mutations Among Newly HIV Diagnosed Neonates and Infants From Mozambique
Arne Kroidl
Germany
#3 - Low-Level Viremia Leads to Increased Risk for Virologic Failure in Children and Adolescents Living With HIV on Antiretroviral Therapy in Sub-Saharan Africa (CLOVES): A Multicenter, Retrospective Cohort Study
Kevin P. McKenzie
Tanzania
#4 - Viral Failure in Children and Adolescents Living With HIV on Dolutegravir (DTG) in Europe and Thailand
Karen Scott
United Kingdom
#5 - Preliminary Safety, Efficacy, and Acceptability of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in Children and Infants From 1 Month Old Weighing 6–<14 KG
Carina Rodriguez
United States
#6 - Interrupting ART in Children: Looking at Neurocognitive Functioning at School-Going Age
Janice Buckley
South Africa
Session 3: Comorbidities / Coinfections -
Resurgence of Congenital Syphilis
Juan Carlos Salazar, MD, MPH
University of Connecticut / Connecticut Children’s, United States
#7 - Progress toward Triple Elimination of Mother-to-Child-Transmission of HIV, HBV, and Syphilis: A 12-months Retrospective Analysis of Testing Coverage in Antenatal Care Clinics in Cameroon
Tchounga Boris Kevin
Cameroon
#8 - Causes of Death Among Infants Living With HIV and Hospitalized With Severe Pneumonia in Sub-Saharan African Countries: Preliminary Results From the EMPIRICAL Trial
Lola Madrid
Spain
#9 - In-Utero Exposure to High TFV-DP Concentrations Is Not Associated With Growth Anthropometrics in HIV Unexposed Breastfed Infants in South Africa: A Post Hoc Analysis of the CAP 016 PrEP in Pregnancy RCT
Kimesh Naidoo
South Africa
#10 - DTG-Based ART Is Not Associated With Excessive Weight Gain in Children: 192 Weeks Follow-up in the ODYSSEY Randomised Trial
Anna Turkova
United Kingdom
HTLV-1 in Pregnant Women: Epidemiology, Risk of Perinatal Transmission, and Potential Prevention
Graham Taylor, MD
Imperial College London, United Kingdom
Clinical Case Presentations
Suvaporn Anugulruengkitt, MD, PhD
Chulalongkorn University, Thailand

Saturday, 20 July 2024

Session 4: Prevention of New Pediatric HIV Infections (and Improving Maternal Health) -
What is New on CAB-LA in Pregnancy: Progress on Implementation and Surveillance of Pregnancy Outcomes
Friday Saidi, MD Mmed
UNC Project Malawi / University of North Carolina at Chapel Hill, United States
The Changing Landscape of Breastfeeding and HIV in High-Income Settings
Karoline Aebi-Popp, PD, MD, MSc
University Hospital Bern, Switzerland
Ulrich von Both, MD, FRCPCH
Dr. von Hauner Children's Hospital, Germany
#11 - Pregnancy and HIV Status Among Pregnant Adolescent Girls and Young Women in Eight EGPAF-Supported Countries
Cosima Lenz
United States
#12 - The Effect of STI Screening During Pregnancy on Vertical Transmission of HIV and Adverse Pregnancy Outcomes in South Africa: A Modelling Study
Dorothy Chiwoniso Nyemba
South Africa
#13 - High Vertical Transmission Rate Among HIV-Exposed Infants up to 9 Months of Age Born to Newly Identified Breastfeeding Women Tested at the Well-Child Clinic: Results From a Pilot in Mozambique
Aleny Couto
Mozambique
#14 - Safety Outcomes Among Infants Whose Mothers Used Dapivirine Vaginal Ring or Oral PrEP During Pregnancy (MTN- 042/DELIVER)
Lee Fairlie
South Africa
#15 - Pharmacokinetics and Safety of Dolutegravir in Neonates Exposed to HIV-1 (IMPAACT 2023)
Hardik Chandasana
United States
Debate: No Infant Antiretroviral Prophylaxis for Infants Born to Mothers with HIV Who Are Virally Suppressed
Jason Brophy, MD, MSc, DTM, FRCPC
Children's Hospital of Eastern Ontario, Canada
Short Oral Poster Presentations
#21- Hospital Outcomes From a Cohort of Mozambican HIV-Exposed Uninfected and HIV-Unexposed Infants
Chris Buck
United States
#22 - Trends in Infant HIV Positivity and Linkage to ART among HIV-Exposed Infants Aged <12 Months in PEPFAR-Supported Programs, FY2018-FY2023
Elizabeth M. Rabold
United States
#23 - Genotypic Resistance to Integrase Inhibitors, Protease Inhibitors and Tenofovir Alafenamide Is Uncommon in Children With Virological Rebound in the CHAPAS-4 Randomised Trial of Second-Line Antiretroviral Therapy for Children With HIV in Africa
Cissy Kityo
Uganda
#24 - In-Utero Exposure to High Tenofovir Concentration Is Associated With Lower Bone Mineral Content in HIV-Unexposed Infants
Kimesh L Naidoo
South Africa
Industry-Supported Symposium -
Towards HIV Cure and Control in Children and Adolescents Everywhere: Past, Present, and Future
Session 5: Adolescents and Young Adults -
The PMPH Center Munich – Providing Better and Holistic Care to Migrant Children and Adolescents
Ulrich von Both, MD, FRCPCH
Dr. von Hauner Children's Hospital, Germany
#16 - A Multi-Country Analysis of HIV Testing Strategies for Identifying Adolescents Living With HIV
Deborah Carpenter
United States
#17 - Findings From the Todurujo NA Kadurok (Empowering Youth) HIV Self-Testing and Edutainment Comic Randomized Controlled Trial With Refugee Youth in a Humanitarian Setting in Uganda
Carmen Logie
Canada
#18 - Concerning Lack of Virological Suppression in Plasma and Cerebrospinal Fluid in Adolescents on Long-term Early Antiretroviral Therapy
Barbara Laughton
South Africa
#19 - Adolescents and Young Adults with HIV Using Long-Acting Injectable Cabotegravir/Rilpivirine as a Standard of Care: Outcomes of the Observational Cohort at 26 months
Tierra Williams
United States
Effectiveness and Safety of Tenofovir Alafenamide Fumarate (TAF)-Based Therapy Compared to Tenofovir Disoproxil Fumarate (TDF)- And Abacavir (ABC)-Based Therapy in Children and Adolescents Living With HIV (CALHIV) in the European Pregnancy and (...)
Elizabeth Chappell
United Kingdom
Transition of Youth Living With HIV to Adult Care: High-Resource Country Experience
Caroline Foster, MD
Imperial College London, United Kingdom
Transition of Youth Living With HIV to Adult Care: Low-Resource Country Experience
Anthony Enimil, MD
Komfo Anokye Teaching Hospital (KATH) / Kwame Nkrumah University of Science and Technology, Ghana
General
Welcome

The 16th International Workshop on Pediatrics & HIV took place in a hybrid format from 19-20 July 2024 in Munich, Germany.

The International Workshop on Pediatrics & HIV 2025 will take place from 11-12 July 2025 in Kigali, Rwanda.

Although we have witnessed a dramatic global scale-up of antiretroviral treatment (ART) as well as efforts to prevent vertical HIV transmission in the last decade, there were 150,000 new pediatric infections in 2021 and an estimated 1.68 million children <15 years of age living with HIV. Children are substantially less likely than adults to be diagnosed, initiate treatment, and achieve durable viral suppression. Currently, only 54% are receiving ART, and treatment of pediatric HIV, particularly in infants and young children, remains complex and problematic, with continued use of suboptimal ART formulations and regimens. 

Furthermore, adolescents are one of the most rapidly growing populations with HIV; in 2021, there were an estimated 410,000 new HIV infections among young people aged 15- 24 years, accounting for 27% of all new HIV infections globally. HIV infections among adolescent girls and young women are 65% higher than among adolescent boys and young men of the same age, with 4,900 new infections occurring in young women weekly. HIV remains one of the leading causes of death among adolescents living in Africa and among the top 10 causes of death in adolescents globally. The uptake of HIV testing among adolescents has remained low. Programs continue to struggle to reach and retain adolescents in care, and adherence to treatment has special challenges, particularly among those with perinatal infection aging up into adolescence and young adulthood. 

As research to improve pediatric HIV diagnosis and care is ongoing, new scientific questions of critical importance have also emerged. In settings with mature ART programs, an increasing proportion of new pediatric infections is attributed to women acquiring HIV infection during pregnancy and breastfeeding, periods of markedly increased risk of HIV acquisition for the mother. With the scale-up of ART for PMTCT, the prevalence of pre-treatment antiretroviral (ARV) drug resistance, particularly to non-nucleoside reverse transcriptase inhibitor drugs, has escalated among newly diagnosed infants, jeopardizing ART effectiveness. Additionally, with more than 1.3 million pregnant women globally receiving ART, there are increasing concerns about the long-term impact of in utero and postnatal exposures to medications for those children who escape HIV. 

Currently, the global population of HIV-exposed uninfected children and adolescents is estimated at 14.8 million, including over 8 million with in-utero ARV exposure. An initial early report of an association with periconception dolutegravir exposure and increased risk of neural tube defects, which upon an increase in the number of periconception exposures subsequently is no longer found, has underscored the need for ongoing attention to surveillance of safety of ARVs in pregnancy. Innovation in early infant diagnosis such as point-of-care tests has facilitated earlier identification of HIV infection during infancy, providing exciting new opportunities to study acute infection and very early treatment in neonates and promising remission strategies. However, despite the critical importance of these topics, research in pediatric, adolescent, and maternal HIV infection is often neglected at major scientific HIV conferences. 

Therefore, in collaboration with leading experts in the field, we have established a highly focused international workshop on the prevention and treatment of pediatric HIV. The overall objective of the International Workshop on HIV & Pediatrics is to stimulate research that will advance prevention and treatment strategies for infants, children, and adolescents. 

Local Co-Chairs 2024
Workshop Chairs
General Information 
Who Should Attend?
- Researchers

- Clinicians

- Nurses

- Industry specialists working in academic settings, hospitals, and non-governmental organizations (NGO)
Meeting Objectives
The meeting aims at:

- Enhancing communication and encouraging collaboration between junior and senior investigators, north and south, and academia, governmental public health agencies, and industry to promote advances in HIV prevention and care in children, adolescents and families.

- Disseminating knowledge and data exchanged by workshop participants beyond the audience of the live event through posting of all presentations on the meeting website, thus maximizing the impact of the meeting by reaching the whole HIV research community.

- Providing updates on the latest research on new pediatric antiretroviral drugs and treatment and prevention strategies in children and adolescents.

- Understanding how to optimize recognition and treatment of advanced HIV disease in children and adolescents.

- Providing updates on new strategies for HIV prevention in children, adolescents and pregnant women, including long-acting antiretroviral agents and HIV vaccines.

- Evaluating effectiveness of and gaps in programs for the prevention of perinatal HIV transmission and interventions to improve such programs.

- Sharing results of implementation science research on how to optimally implement programs for prevention or treatment of HIV in infants, children, adolescents and pregnant women in developing countries.

- Understanding the complications of long-term HIV infection and its therapy, to enable improved management of HIV in children and adolescents.

- Providing update on prevention or treatment of coinfections, such as tuberculosis and hepatitis C, in children and adolescents.
AIDS 2024
Pediatrics & HIV 2024 is an AIDS 2024 Affiliated Independent Event.
Practical Information 
Venue
Pediatrics & HIV 2024 will take place at the H4 Hotel München Messe: Konrad-Zuse-Platz 14, 81829 München, Germany
Badges
All participants are requested to wear the badge at all times during the workshop to ensure admission to the meeting.
Certificate of Attendance
A certificate of attendance will be sent to you after successfully completing the program and post-meeting survey.
Language
The official language of the workshop is English.
Translation will not be provided.
Enduring Materials
Enduring materials will be available here 3 weeks after the conclusion of the workshop.
Disclaimer
This workshop is intended for educational purposes only and aims to offer participants the opportunity to share information. The Organizing Secretariat of this event, Virology Education, cannot accept any liability for the scientific content of the sessions or for any claims which may result from the use of information or publications from this meeting. Virology Education disclaims all liability for injuries or losses of whatever nature incurred by individuals attending the workshop.
Liability and Insurance
By registering for the workshop participants agree that the organizers do not accept responsibility for medical-, travel- or personal insurance. Participants are advised to take out their own insurance policies.
Photographs, Audio, and Video Recording
Photographs, audio, and video recordings are not permitted at the official meeting sessions. Only the official medical writer appointed by the organization may make recordings. All presentations will be posted here 3 weeks after the workshop is finished, provided the speaker has given permission to do so.
Code of Conduct
All attendees, speakers, co-organizers, partners, endorsers, suppliers, volunteers, and employees at any of our programs are expected to observe our Code of Conduct. We cannot tolerate any form of discrimination, harassment, disrespect, or the marginalization of those involved in our programs. All participants of VE and AME-organized programs are expected to treat others with dignity and respect at all times.

Any individual who feels discriminated against, harassed, disrespected, or marginalized is encouraged to report the incident(s) to VE and AME via info@amededu.com or to one of our on-site personnel.
Any participant who is found to have exhibited any inappropriate conduct or behavior against others may be removed from the program.
Symposium
Towards HIV Cure and Control in Children and Adolescents Everywhere: Past, Present, and Future
Symposium Program | 20 July 2024 -
From CHER to Cure: How a Pivotal Trial Helped to Shape the HIV Cure/Control Agenda in Children & Adolescents
Mark Cotton, MD, PhD
Tygerberg Children’s Hospital (TCH), Stellenbosch University (SU), South Africa
Update on Cure Agenda
Deborah Persaud, MD
Johns Hopkins University School of Medicine, United States
Update on Analytic Treatment Interruption Consensus Guidelines for HIV Cure/Control
Mark Cotton, MD, PhD
Tygerberg Children’s Hospital (TCH), Stellenbosch University (SU), South Africa
Committees
Workshop Chairs 2024
Organizing Committee
The members of the Organizing Committee are a group of carefully selected experts and inspirational leaders in their respective fields. They meet frequently to discuss the scientific program of the workshop, identify interesting topics and candidate speakers, and review all submitted abstracts.
Scientific Committee

We are proud to present the members of the committee:

  • Adam Bartlett, BSc, MBBS, MPHTM, PhD, FRACP - Sydney Children's Hospital / Kirby Institute, Australia

  • Jason Brophy, MD, MSc, DTM, FRCPC - Children's Hospital of Eastern Ontario, Canada

  • Ellen Chadwick, MD - Ann & Robert H. Lurie Children’s Hospital of Chicago / Northwestern University Feinberg School of Medicine, United States

  • Tsungai Chipato, MBChB - University of Zimbabwe College of Health Sciences, Zimbabwe

  • Polly Clayden - HIV i-Base, United Kingdom

  • Anita De Rossi, PhD - University of Padova / Istituto Oncologico Veneto (IOV)-IRCCS, Italy

  • Marinella Della Negra, MD, PhD - Hospital Emilio Ribas, Brazil

  • Brian Eley, MD - University of Cape Town, South Africa

  • Albert Faye, PhD - Denis Diderot University, Paris, France

  • Rashida Ferrand, MBBS, FRCP, PhD - London School of Hygiene and Tropical Medicine / Biomedical Research and Training Institute, Zimbabwe

  • Patricia Flynn, MD - St. Jude Children's Research Hospital, United States

  • Tessa Goetghebuer, MD - Office de la Naissance et de l'Enfance / CHU Saint-Pierree, Belgium

  • Ali Judd, PhD, University College London, United Kingdom

  • Valériane Leroy, MD - Inserm, Paris, France

  • Chewe Luo, MD, PhD - UNICEF, United States

  • Dorothy Mbori-Ngacha, MBChB, MMed, MPH - Independent Consultant, Kenya

  • Immaculate Mutisya, MMed - Centres for Disease Control and Prevention, Kenya

  • Sharon Nachman, MD - SUNY Stony Brook / IMPAACT, United States

  • Clare Nourse, AM, BA, MB, BCH, BAO DCH, MRCPI, FRACP, MD - Children's Health Queensland / University of Queensland, Australia

  • Paul Palumbo, MD - Dartmouth-Hitchcock Medical Center, United States

  • Martina Penazzato, MD, MSc, PhD - World Health Organization, Switzerland

  • Kathleen Powis, MD, Massachusetts General Hospital, United States

  • Natella Rakhmanina, MD, PhD, FAAP, FCP, AAHIVS - Elizabeth Glaser Pediatrics AIDS Foundation / Children’s National Hospital, United States

  • Theodore Ruel, MD - UCSF Benioff Children's Hospital San Francisco, United States

  • George Siberry, MD, MPH, FAAP, FPIDS - United States Agency for International Development (USAID), United States

  • Lynda Stranix-Chibanda, MBChB, MMed - University of Zimbabwe, Zimbabwe

  • Tavitiya Sudjaritruk, MD, ScM, PhD - Chiang Mai University, Thailand

  • Graham Taylor, MD - Imperial College, United Kingdom

  • Claire Thorne, BA, MSc, PhD - University College London, United Kingdom

  • Priscilla Tsondai, MBChB and MPH, International AIDS Society, South Africa

  • Marissa Vicari - UNAIDS, Switzerland

  • Rachel Vreeman, MD, MS - Icahn School of Medicine at Mount Sinai, United States

The members of Scientific Committee are hand-picked by the Organizing Committee and the workshop secretariat based on their significant contributions and commitment to the field. They assist the Organizing Committee by providing them with suggestions for speakers and topics. In addition, members of the Scientific Committee participate in reviewing submitted abstracts, and play an active role during the workshop as moderators and/or chairs of sessions.
Endorsers
Support
Platinum Level
Contributor Level

Support Our Initiative
Financial backing helps us deliver an impactful meeting experience to the benefit of healthcare professionals and researchers interested in Pediatrics & HIV.
 
This collaboration plays a vital role in both the organizational as well as scientific success of the program.

To show your commitment to the cause, get in touch with us for a tailored
support package by contacting Ms. Karin Siebelt at Karin.Siebelt@amededu.com.
 
Benefits of Support
By supporting this program, we can offer the following advantages for your company.* Please contact us for the most recent support level benefits for this program.

  • Symposium opportunities
  • Non-commercial interviews with company representatives
  • Verbal acknowledgement during the program 
  • Discounted and complimentary registrations for your representatives
  • Company acknowledgement on digital meeting materials including but not limited to newsletters, flyers, the streaming platform, and our website
  • Company acknowledgement on printed meeting materials including but not limited to banners and the program book
  • Digital and printed advertising opportunities 
  • Social media shout-outs
  • Logo on the conference bag 

 
*Subject to the support level.

Accreditation
Accreditation Statement
EACCME logo

The International Workshop on Pediatrics & HIV 2024, Munich, Germany, Germany 19/07/2024 - 20/07/2024 , has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 12.5 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.


Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at https://edhub.ama-assn.org/pages/applications .

Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College
of Physicians and Surgeons of Canada.

Media
Penta’s Young Reporters at the International Workshop on Pediatrics and HIV 2024

Arriving at the International Workshop on Pediatrics & HIV 2024, we felt a mix of nerves and excitement, knowing we were about to be surrounded by experts who spend their careers understanding and fighting the virus we live with every day. But as Young Reporters, we were determined to make sure we take what we can understand to share with other young people who need this knowledge. 

The presentation by Anna Yakutsk from UNAIDS made us feel that we were not alone, but part of a global community. But it also made us feel sad that so many new infections are still happening. As she spoke about the significant strides made in pediatric HIV and the importance of ensuring access to testing and treatment, we considered that it's one thing to manage the medical side of HIV, but the emotional and social challenges can feel overwhelming. This was later highlighted by a session at the end of Day 2 which showed the impact of what youth-friendly HIV services can do for us. 

One of the most enlightening sessions I attended was on the reasons for resistance of antiretroviral therapy for children. Dr. Natella Rakhmanina explained in such a way that made us feel like we understood what people mean when they say treatment ‘fails’.  Hearing about this has inspired us to think about how we can support young people to talk to their doctors about this experience and the support needed to get through it. We have much to celebrate as new treatments become available, but for some of us, these are not options and this disappointment can be heavy to hold. But the reasons Natella shared helped us understand this better and not feel ashamed about medicine resistance. 

One of us took part in the Youth Panel, which explored the shared stories of young people through diagnosis, transition and their treatment journey. We all felt proud to see the panel share experiences that are shared by many of us living with HIV.  The spirit of resilience and advocacy shone through the session. 

Though we were nervous to attend and did not understand all of the science details, it was a good experience. It gave us hope for the future, a greater understanding of the challenges we face, and a determination to advocate for ourselves and others living with HIV. The knowledge we gained we will share with our peers and it has helped us a lot.

Young Reporters 2024

For more information, you can find the the full article here: https://penta-id.org/news/penta-young-reporters-journey-at-the-international-workshop-on-pediatrics-and-hiv/

young reporters

15th Anniversary of the International Workshop on HIV & Pediatrics
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