- Acute and chronic effects of viral diseases often involve immune-mediated responses, including inflammation, immune activation, and autoimmunity. Therapeutic interventions must often target both ends of the virus-immune system spectrum.
- Statins reduce severe cardiovascular events in people with HIV, even in individuals with low baseline cardiovascular risk.
- Long-COVID immunopathogenesis is complex but its understanding is advancing rapidly. The consequences of immune-mediated damage in long COVID share similarities (and differences) with other post-viral diseases like Ebola and MF/CFS
- Viruses can also trigger autoimmunity. Epstein-Barr Virus is tightly linked with the onset of Multiple Sclerosis through several autoimmune mechanisms. Viral encephalitis also often has an autoimmune background
- Immune therapies targeting the inflammasome or virus-specific CAR-T cells, among others, are advancing towards the cure of different acute and chronic viral diseases
Meeting category
Date(s)
6 Sep 2023 - 7 Sep 2023
Program Language
English
Location
Rockville,
MD,
United States
Meeting type
Hybrid Meeting
Viral Infections & Inflammation Workshop 2023
Related Enduring Materials
Enduring Materials
5 Key Messages from VII Workshop 2022
Program
Day 1, Wednesday 6 September
Opening of the Workshop -
Plenary Talk: Update on the REPRIEVE Trial to Prevent Cardiovascular Events in People with HIV
Session 1: Post-COVID Syndromes -
Viruses, Immune Dysfunction, and ME/CFS
Underlying Mechanisms of Long COVID
Satellite Symposium -
The Impact of Viral Glycoproteins on Inflammation and Immunity
Session 2: Post-infectious Syndromes -
Immune Signatures in Vaccine-Associated Myocarditis
What We Know Now about HIV and Long COVID
Epstein–Barr Virus and Multiple Sclerosis: Which Mechanisms are at Play?
(O_#3) A Role for Inflammasome Activation and Oxidative Stress in Sars-CoV-2 Breakthrough Infection and Symptomatic Rebound
Silvia Lucena Lage
NIH, United States
Day 2, Thursday 7 September
Session 3: Post-acute Sequelae Following Different Infections -
Post-acute Sequelae following Ebola infection
Endogeneous Retroviruses and Inflammation
Session 4: Chronic Viral Infections and Inflammation-related Comorbidities -
HIV, Inflammation, and Macrophages
Inflammation in People with Low Nadir CD4 Counts
Acute Disseminated Encephalomyelitis
Session 5: Interventions Targeting Inflammation and Post-viral Syndromes -
Inflammasome Activation in Severe Cases of COVID-19
Developing CAR T Cells for Use in Chronic HIV Infection
(O_#7) Impact of Glatiramer Acetate Treatment in SIVmac-Infected Macaques
Beatrice Jacqulin
Institut Pasteur, France
Overview
Thank you
We are pleased to look back on a very successful 2nd edition of the Viral Infections & Inflammation Workshop 2023, held from 6 - 7 September in Rockville, Maryland, USA.
The Organizing Committee and organizers would like to thank the speakers, chairs, and all participants for their contribution to this meeting! Special thanks to the workshop support: ViiV Healthcare and Merck. Without their contribution, this workshop would not have been made possible.
About this Program
The Viral Infections & Inflammation Workshop 2023 brought together basic, translational, and clinical researchers to disseminate the latest knowledge in this area and fuel discussion on the many remaining unknowns in order to catalyze future research.
Inflammatory response and cytokine storm in severely ill COVID-19 patients have put a spotlight on the importance of inflammation in viral infections. Prevalence of long-term COVID is also a concern and potentially related to the suboptimal function of the immune system. Yet, these concerns are not unique to COVID-19. In the case of HIV for instance, despite remarkable improvements in antiretroviral therapy, immune reconstitution remains limited in some patients even a long time after treatment initiation. Exhaustion of primary immune resources due to persistent activation and inflammation drives premature immune aging and impacts life expectancy.
Although HIV and SARS-CoV-2 are fundamentally different infections with distinct long-term consequences, underlying mechanisms that drive those complications might be common. Common underlying mechanisms imply the possibility to employ similar therapeutic interventions. For instance neutralizing antibodies, antiviral drugs, and therapeutic vaccines to eliminate the persistent virus or anti-inflammatory drugs to ameliorate chronic inflammation.
General Information
Who Should Attend?
- Infectiologists;
- (Clinical) virologists;
- Immunologists;
- Microbiologists; and
- Researchers
- (Clinical) virologists;
- Immunologists;
- Microbiologists; and
- Researchers
Meeting Objectives
This meeting aims to:
-Provide a global platform to exchange knowledge across different disciplines involved in research on mechanisms of virus-mediated inflammation;
- Gather basic, translational, and clinical researchers to stimulate discussion on remaining unknowns;
- Translate the data into clinical guidance; and
- Increase the visibility of junior investigators and their research thereby facilitating a generation of future leaders in the field.
-Provide a global platform to exchange knowledge across different disciplines involved in research on mechanisms of virus-mediated inflammation;
- Gather basic, translational, and clinical researchers to stimulate discussion on remaining unknowns;
- Translate the data into clinical guidance; and
- Increase the visibility of junior investigators and their research thereby facilitating a generation of future leaders in the field.
Learning Objectives
After participating in this activity, participants will be able to:
- Increase understanding of mechanisms underlying persistent inflammation in viral diseases;
- Outline clinical studies aimed at determining molecular, cellular, and immunological mechanisms of virus-related diseases; and
-Understand clinical data evaluating the potential therapeutic interventions.
- Increase understanding of mechanisms underlying persistent inflammation in viral diseases;
- Outline clinical studies aimed at determining molecular, cellular, and immunological mechanisms of virus-related diseases; and
-Understand clinical data evaluating the potential therapeutic interventions.
Practical Information
We trust that the following information will assist you in organizing your participation for the Viral Infections and Inflammation Workshop 2023.
Venue
The workshop took place at NIH/ NIAID facilities located in 5601 Fishers Lane, Rockville, MD, 20852, United States.
Foreign nationals do not need prior clearance to attend the meeting at NIH/NIAID. However, showing a valid passport is required. Non-NIH US citizens attending the meeting will have to show a valid government ID.
Foreign nationals do not need prior clearance to attend the meeting at NIH/NIAID. However, showing a valid passport is required. Non-NIH US citizens attending the meeting will have to show a valid government ID.
Accommodation
Accommodation is not included in the registration fee.
Badges
All participants are requested to wear the badge at all times during the conference to ensure admission to the meeting.
Certificate of Attendance
A digital certificate of attendance will be sent to participants that have successfully completed the program and post-meeting survey.
Language
The official language of the workshop is English. Translation will not be provided.
Disclaimer
This workshop is intended for educational purposes only and aims to offer participants the opportunity to share information. The Organizing Secretariat of this event, Virology Education, cannot accept any liability for the scientific content of the sessions or for any claims which may result from the use of information or publications from this meeting. Virology Education disclaims all liability for injuries or losses of whatever nature incurred by individuals attending the workshop.
Liability and Insurance
By registering for the workshop, participants agree that the organizers do not accept responsibility for medical-, travel- or personal insurance. Participants are advised to take out their own insurance policies.
Photographs, Audio, and Video Recording
Photographs, audio, and video recordings are not permitted at the official meeting sessions. Only the official medical writer appointed by the organization may make recordings. All presentations will be posted here as soon as possible after the workshop is finished, provided the speaker has given permission to do so.
Code of Conduct
All attendees, speakers, co-organizers, partners, endorsers, suppliers, volunteers, and employees at any of our programs are expected to observe our Code of Conduct. We cannot tolerate any form of discrimination, harassment, disrespect, or the marginalization of those involved in our programs. All participants of VE and AME-organized programs are expected to treat others with dignity and respect at all times.
Any individual who feels discriminated against, harassed, disrespected, or marginalized is encouraged to report the incident(s) to VE and AME via info@amededu.com or to one of our on-site personnel.
Any participant who is found to have exhibited any inappropriate conduct or behavior against others may be removed from the program.
Any individual who feels discriminated against, harassed, disrespected, or marginalized is encouraged to report the incident(s) to VE and AME via info@amededu.com or to one of our on-site personnel.
Any participant who is found to have exhibited any inappropriate conduct or behavior against others may be removed from the program.
Symposium
Day 1 - Wednesday, 6 September 2023
Satellite Symposium: The Impact of Viral Glycoproteins on Inflammation and Immunity -
Immunopathology of Viral Encephalitis
Immune Responses to AAV in the Context of Gene Therapy
Host and Viral Glycoproteins in HIV Neuropathogenesis
Committees
The members of the Organizing Committee are a group of carefully selected experts and inspirational leaders in their respective fields. They meet frequently to discuss the scientific program of the workshop, identify interesting topics and candidate speakers, and review all submitted abstracts.
Support
Gold Level
Silver Level
Satellite Symposium
The Satellite Symposium: The Impact of Viral Glycoproteins on Inflammation and Immunity is supported by an independent educational grant from ViiV Healthcare.
ViiV Healthcare was not involved in the development of content or selection of faculty for this educational activity.
Support Our Initiative
Financial backing helps us deliver an impactful meeting experience to the benefit of healthcare professionals and researchers interested in HIV and inflammation.
This collaboration plays a vital role in both the organizational as well as scientific success of the program.
To show your commitment to the cause, get in touch with us for a tailored
support package by contacting Ms. Federica Ressa at Federica@amededu.com or call +31 30 2307147.
Benefits of Support
By supporting this program, we can offer the following advantages for your company.* Please contact us for the most recent support level benefits for this program.
- Symposium opportunities
- Non-commercial interviews with company representatives
- Verbal acknowledgement during the program
- Discounted and complimentary registrations for your representatives
- Company acknowledgement on digital meeting materials including but not limited to newsletters, flyers, the streaming platform, and our website
- Company acknowledgement on printed meeting materials including but not limited to banners and the program book
- Digital and printed advertising opportunities
- Social media shout-outs
- Logo on the conference bag
*Subject to the support level.
Endorsers
The Viral Infections & Inflammation Workshop 2023 was endorsed by the following organizations:
Media
2023 Highlights
Hear Prof. Roger Paredes, MD, PhD (Hospital Germans Trias & IrsiCaixa AIDS Research Institute, Spain) deliver an insightful summary for clinicians on the take-home messages from the 2nd edition of the Workshop!
Previous Editions
Language
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