Biography

Dr. Grattoni is the Frank J. and Jean Raymond Centennial Chair, and Chairman and Professor of the Center for BioNanoengineering at the Houston Methodist Hospital, and Professor in the Departments of Surgery and Radiation Oncology. He is also an Adjunct Professor at the Texas A&M School of Medicine. His research focus is the development and clinical translation of long-acting implantable nanofluidic platforms for HIV prevention and treatment. These technologies enable sustained, controlled delivery of antiviral agents for pre-exposure prophylaxis (PrEP) and therapy, addressing adherence challenges to transform HIV care globally. Complementary research include technologies for cell transplantation and immune-cell engineering, designed to create immune-modulated microenvironments that support long-term cell survival for applications such as type 1 diabetes. Additional efforts encompass intratumoral immunoradiotherapy and remotely controlled drug delivery and electrokinetic nanofluidics. With ISS National Lab support, he established the Center for Space Nanomedicine at Houston Methodist to investigate nanomedicine in microgravity. Dr. Grattoni has been funded by Breakthrough T1D, DoD, NASA, NIH (NIAID, NIDDK, NIGMS, NCI), ISS National Laboratory, USAID, the Gates Foundation, and others. He is founder and scientific advisor of Continuity Biosciences and a Scientific Advisory Board member of the Diabetes Research Institute at the University of Miami.