Biography

With the success of antiretroviral therapy and improved survival of HIV patients, non-AIDS – and especially age-related – complications are becoming the greatest cause of morbidity and mortality. He has conducted analyses of the rates and determinants of non-AIDS complications among people with HIV and the factors associated with increased risk, including the impact of combination antiretroviral therapy. This has included the analyses of 1) risk factors of non-AIDS defining malignancies, in the pre-HAART and HAART era, and the role of antiretroviral exposure and statin therapy; 2) risk factors and predictors of cardiovascular disease including the role of abacavir and lipid-lowering therapy; and the risk factors and complications of weight gain on ART; 3) predictors of bone mineral loss among HIV-infected patients, including the role of antiretroviral therapy and HCV co-infection.