Immune Non-Responders - A Remaining Unmet Need | Satellite Symposium at EACS 2021
Welcome
Despite remarkable improvements in antiretroviral therapy (ART), immune reconstitution remains limited in some patients even a long time after ART initiation and impacts their life expectancy. This is of particular concern for young people that acquire HIV perinatally, or early in their life. While early ART initiation holds promise to improve immune capacity, late presenters, and underdiagnosis remain of considerable concern. Cellular and molecular mechanisms underlying HIV-associated immune activation and inflammation remain extensively studied, as well as adequate biomarkers to monitor ART-induced repair of damaged tissue. This program aims at bringing together basic, translational, and clinical researchers to disseminate the latest knowledge in this area, and fuel discussion on the many remaining unknowns to catalyze future research.