1st International Workshop On Long Acting Anti-Infectives (LAAI) 2025
09:00
Opening & Session 1: Advancing Long-Acting Anti-Infectives: Regulatory Insights and Clinical Impact
09:05
Welcome to New Orleans
09:10
Long-Acting Anti-Infectives: Where Do We Stand?
Charles Flexner
09:30
Pharmacological Considerations of Routes of Administration for Long-Acting Injectable Products
Simone Perazzolo
09:50
Regulatory Considerations for Long-Acting Anti-Infectives: Challenges and Opportunities
Kellie Schoolar Reynolds
11:10
Session 2: Long-Acting Options for HIV Prevention
11:10
Current and Future Perspectives in HIV Prevention: Approved Drugs and Therapies in Development
Richard Elion
11:30
Long-Acting Antiretroviral Monoclonal Antibodies: Revolutionizing HIV Prevention
Huub Gelderblom
11:50
Getting It Right This Time: The Impact of PEPFAR Stop Work Orders on Injectable PrEP and Implications for LEN Rollout
Stacey Hannah
12:05
#1 Proof-of-Concept Study of Oral VH4004280, a New HIV-1 Capsid Inhibitor
Abstract
Paul Benn
14:45
Session 3: Long-Acting Treatment Options for HIV
14:45
Implementation Challenges in LMICs
Noela Owarwo
15:05
Laboratory Considerations in the Age of Long-Acting Agents: A Focus on HIV Resistance
Mark Marzinke
15:25
#101 LB-#1 What Do Early Adopters of Long-Acting Injectable Cabotegravir-Rilpivirine Think About It?
Abstract
Katerina Christopoulos
15:35
#2 Utilization and Effectiveness of Cabotegravir + Rilpivirine in People with HIV (PWH) with Viremia at Treatment Initiation
Abstract
Richard Elion
15:45
#3 Novel Ultra-Long-Acting Injectable Formulations of Bictegravir
Abstract
Xiaohong Qi
16:45
Session 4: Navigating Long-Acting Anti-Infective Therapies: Clinical Evidence and Practical Application in Key Populations
16:45
Pharmacokinetic Considerations of Long-Acting Anti-Infective Administration During Pregnancy
Robert Bies
17:05
The Long-Acting Anti-Infective Agents for Children and Adolescents: Are We Nearly There Yet?
Natella Rakhmanina
17:25
#4 Facilitators and barriers to long-acting injectable antiretroviral therapy uptake among youth living with HIV in Cape Town, South Africa: A COM-B analysis
Abstract
Sheree Schwartz
17:35
#5 Cabotegravir and Rilpivirine in Pregnancy: A Multi-Center Study Evaluating HIV viral suppression, Perinatal and Neonatal Outcomes
Abstract
William Short
17:45
#102 LB-#2 Twice-yearly lenacapavir PrEP in cisgender gay men, transgender women and men, and gender-diverse people (PURPOSE 2)
Abstract
Meredith E Clement
18:00
Poster Viewing Session
18:00
#10 Black Transgender and Cisgender Women’s Experiences With PrEP and Reasons for Choosing Injectable PrEP
Abstract
Nanlesta Pilgrim
18:00
#11 PILLAR Month 12 Clinical Results: Zero HIV Acquisition and High Persistence With CAB LA for PrEP
Abstract
Heidi Swygard
18:00
#12 Feasibility of Delivering Long-Acting Antiretroviral Injectables to Key Populations in Uganda: Lessons from HIV Prevention Programs
Abstract
JIMMY SSENGENDO
18:00
#13 Long-Acting PrEP Awareness and Interest among Black and Hispanic Men in the US
Abstract
Supriya Sarkar
18:00
#14 Evaluation of Patient Experience and Treatment Tolerability in the Phase 2b Study of VH3810109 (N6LS) and Cabotegravir Long-Acting Injections for HIV Treatment
Abstract
Irina Kolobova
18:00
#15 Higher real-world adherence and persistence with long-acting cabotegravir plus rilpivirine (CAB+RPV LA) compared to oral antiretroviral therapy (ART) among people with HIV (PWH) in the US: the ABOVE study
Abstract
Paula Teichner
18:00
#16 Similar Virologic Outcomes and Isolated Viremic Event (Blips, Low-Level Viremia, Suspected Virologic Failure) Frequency Between Oral and Long-Acting Antiretroviral Therapy: Pooled Analysis of Phase 3/3b Cabotegravir + Rilpivirine Long-Acting Studies
Abstract
Kimberley Brown
18:00
#17 Patient Preferences for Long Acting Injectable and Oral ART: A Discrete Choice Experiment in the US
Abstract
Irina Kolobova
18:00
#18 Clinical Outcomes at Month 12 After Initiation of Cabotegravir and Rilpivirine Long Acting (CAB+RPV LA) in an Observational Real-World Study (BEYOND)
Abstract
Paula Teichner
18:00
#19 Comparison of treatment-emergent resistance associated mutations among single tablet regimens and cabotegravir+rilpivirine for the treatment of virologically suppressed people with HIV: A Systematic Literature Review and Network Meta-Analysis
Abstract
Nathan Unger
18:00
#20 High and comparable efficacy between CAB+RPV LA and oral ART across a range cardiovascular risk profiles and statin use: A post hoc analysis of CAB+RPV LA Phase 3/3b studies
Abstract
Kimberley Brown
18:00
#21 Evaluation of the interest of Cameroonian adolescents living with HIV/AIDS to long-acting antiretroviral treatment: the CIPHER-ADOLA Study
Abstract
Yagai Bouba
18:00
#22 Patient Experiences at Month 6 After Initiation of Cabotegravir Long-Acting (CAB LA) for PrEP in the First Male Gender Concordant Implementation Science Trial (PILLAR) in the US
Abstract
Kim Nezianya
18:00
#23 Comparative analysis of screening and preventative measures and healthcare resource utilization among people with HIV receiving long-acting cabotegravir plus rilpivirine or oral antiretroviral therapy in the US: the ABOVE study
Abstract
Paula Teichner
18:00
#24 Feasibility, Fidelity, and Effectiveness of Administering CABENUVA in Infusion Centers
Abstract
Maggie Czarnogorski
18:00
#26 Impact of introduction of Long-Acting Injectable Antiretroviral on Viral Suppression Among People with HIV and Adherence Challenges in a Low-Barrier, Support-Intensive Program
Abstract
Kellie Hawkins
18:00
#27 Cost-Effectiveness of Cabotegravir Long-Acting for HIV Pre-Exposure Prophylaxis (PrEP): A Systematic Review of Modelling Studies
Abstract
Fortune Effiong
18:00
#28 Maintained Virologic Suppression with Cabotegravir-Rilpivirine in PLWH on Dialysis
Abstract
Hector Bolivar
18:00
#29 How Do Injection Site Reactions Influence Preferences for Long-Acting Injectable HIV Treatment?
Abstract
Paul Benn
18:00
#30 Expanding the use of long-acting HIV treatment: will hepatitis B have a field day?
Abstract
Wubbo de Boer
19:30
Networking Dinner