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Meeting category
Date(s)
8 Nov 2018 - 9 Nov 2018
Location
Amsterdam, Netherlands
Organizer

International Workshop on Clinical Pharmacology of Anticancer Drugs (ICPAD) 2018

Related Enduring Materials

Enduring Materials

Day 1 - Thursday, 8 November 2018

Session 1: Pharmacological challenges of immunotherapeutics -
Biomarker in immuno-oncology, are we close? (Not yet available)
Josep María Piulats
Josep María Piulats, MD, PhD
Catalan Institute of Oncology, Spain
Correlation between nivolumab exposure and treatment outcome in NSCLC
Sander Bins
#O1
Session 2: Dose individualization approaches -
Cytotoxic agents
Markus Jörge
Markus Jörger, MD, PhD
Cantonal Hospital, Switzerland
Targeted agents and monoclonal antibodies
Joseph Ciccolini
Joseph Ciccolini, PharmD, PhD
Aix-Marseille Université, France
Using pharmacogenetics to improve drug therapy: a 12 year experience with clinical implementation (Not yet available)
Ron van Schaik
Ron van Schaik, PhD, FACB
Erasmus Medical Centre, the Netherlands
Abstract presentation -
A pharmacometric framework for dose individualisation of sunitinib in GIST
Maddalena Centanni
#O2
Therapeutic drug monitoring as a tool to reduce the occurrence of paclitaxel-associated peripheral neuropathy in patients with advanced NSCLC (Not yet available)
Francis Ojara Williams
#O3
Abstract-driven presentations -
Epigenetic Regulation of OCTN1-mediated Cytarabine Transport in Acute Myeloid Leukemia
Jason Anderson
USA
Comprehensive Pan-Cancer analysis of somatic mutations in drug transporters to reveal acquired and intrinsic drug resistance in 3149 metastatic cancer patients
Wesley Van De Geer
Netherlands

Day 2 - Friday, 9 November 2018

Session 3: Combination therapy – old school is becoming new school again -
Immunotherapy of prostate cancer and urothelial cancer. Future directions
Winald Gerritsen
Winald Gerritsen, MD, PhD
Radboud University, the Netherlands
Rationale for selecting combinations with immunotherapy
Howard Gurney, MBBS, FRACP
Westmead Hospital, Australia
Session 4: Drug-Drug / Drug-Food / Drug-environmental interactions -
Drug-Drug interactions with targeted oncolytics (in particular PPIs and TKIs)
Ron Mathijssen, MD, PhD
Department of Medical Oncology, Erasmus MC, Netherlands
Pharmacotherapy of Comorbities: Cancer Patients with HIV/AIDS
Michelle Rudek, PharmD, PhD
Johns Hopkins University, United States
Drug-drug interaction management with DDI-Predictor
Michel Tod
Michel Tod, PharmD, PhD
Faculté de Médecine Lyon-Sud, University of Lyon, France
Abstract presentation -
Novel online drug-drug interaction resource reveals clinically relevant interactions in >20% of the searches
Stefanie Krens
#O5
Food intervention to make therapy with pazopanib more patient friendly and affordable
Floor Lubberman
#O6
Session 5: Approaches to shorten phase II studies by the use of different read out endpoints -
The value of surrogate endpoints in the benefit-risk assessment of new drugs
Gabe Sonke
Gabe Sonke, MD, PhD
Netherlands Cancer Institute, the Netherlands
Clinical relevance of liquid biopsy in cancer patients
Catherine Alix-Panabières
Catherine Alix-Panabières, PhD
University Medical Centre of Montpellier, France
Abstract presentation -
A Pharmacokinetic-Pharmacodynamic binding model of Bevacizumab to VEGF as a tool to optimize treatment
Apostolos Papachristos
#O7
A generalisable pharmacokinetic-pharmacodynamic (PKPD) model of savolitinib, a novel MET tyrosine kinase inhibitor, to explore extent and duration of target inhibition required for optimal efficacy across a range of tumour xenograft models
Rhys Jones
#O8
Session 6: PK/PD studies and new strategies -
How studies can be optimized by simultaneous use of PK/PD outcome measurement?
Alwin Huitema
Alwin Huitema, PharmD, PhD
Netherlands Cancer Institute, the Netherlands
Abstract presentation -
The relationship between busulphan AUC and the incidence of sinusoidal obstruction syndrome in haematopoietic stem cell transplants
Parth Upadhyay
#O9
Translation from mouse to human of pharmacokinetic-pharmacodynamic modelling of biomarker response – learnings from the AstraZeneca Oncology portfolio
Rhys Jones
#10
Overview
Welcome

We are pleased to look back on a very successful the 3rd International Workshop on Clinical Pharmacology of Anticancer Drugs (ICPAD), held on the 8th and 9th November 2018 in Amsterdam, the Netherlands. 

The Organizing Committee and organizers would like to thank the speakers, chairs and all participants for their contribution to this meeting! Special thanks to the workshop sponsors: AstellasPfizer, and BJCP. Without their contribution this workshop would not have been made possible.

We look forward to seeing you again next year at the 4th International Workshop on Clinical Pharmacology of Anticancer Drugs (ICPAD), tentatively scheduled on 21-22 November 2019, in the Netherlands.

The Organizing Committee