Day 1 - Wednesday, 16 October 2019
Meeting category
Date(s)
16 Oct 2019 - 17 Oct 2019
Organizer
Platinum Level Support
Sponsor logos
International Workshop on Microbiome in HIV Pathogenesis, Prevention and Treatment 2019
Related Enduring Materials
Enduring Materials
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Program
Keynote Lecture 1 -
Omics Approaches to Study the Host-Vaginal Microbiota Interactions (No permission to publish slides)
Jacques Ravel, PhD
University of Maryland School of Medicine, USA
Session 1: Pathogenesis -
Chairs
Jason Brenchley, MA, PhD
National Institutes of Health, USA
Sergio Serrano-Villar, MD, PhD
University Hospital Ramón y Cajal, Madrid, Spain
Host-Microbiome Interactions at the Oral Mucosal Barrier
Niki Moutsopoulos, DDS, Phd
NIH/NIDCR, USA
Regulation of intestinal viral infections by the microbiota
11:15 EDT
Abstract Presentation Slot
Fecal microvesicles differentially influence translocating bacterial taxa after SIV infection (No permission to publish slides)
Alexandra Ortiz
Glycomic determinants of gut microbial dysbiosis and translocation during suppressed HIV infection (No permission to publish slides)
Leila Giron
Session 2: Transmission & Prevention -
Chairs
Gilda Tachedjian, BSc (Hons), PhD
Burnet Institute, Melbourne, Australia
Jim A. Turpin, PhD
NIH, USA
13:30 EDT
Multi-omic assessment of interactions between an intravaginal ring delivering TDF and FTC and the vaginal microbiome in a Phase 1 randomized, placebo-controlled clinical trial
14:00 EDT
Metaproteomics to understand mucosal inflammation associated with HIV acquisition risk in young African women
14:30 EDT
Update on live biotherapeutic trials to prevent vaginal dysbiosis and HIV
15:00 EDT
Abstract Presentation Slot
Host genetic determinants of the vaginal microbiome and bacterial vaginosis in Kenyan women
Supriya Mehta
Elevated fecal inflammatory biomarkers in HIV-/+ MSM associate with gut microbiota
Jennifer Schneider
DAY 2 - Thursday, 17 October
Session 3: Comorbidities -
Chairs
Roger Paredes, MD, PhD
IrsiCaixa AIDS Research Institute, Badalona, Catalonia, Spain
Peter Perrin
-
9:15 EDT
The relationship between the gut microbiome, inflammation and metabolic disease in HIV infected and high risk populations
9:45 EDT
Endotoxemia, inflammation and HIV: Revisiting an old concept
10:15 EDT
Abstract Presentation Slot
Colonic microbiota is altered in treated HIV infection independently of sexual practice and correlates with HIV disease progression (No permission to publish slides)
Ivan Vujkovic-Cvijin
Metformin treatment and gut microbiota in non-diabetic persons living with HIV (No permission to publish slides)
Stéphane Isnard
Session 4: Vaccines -
Chairs
Que Dang, PhD
NIH, USA
Jim Kublin
-
11:45 EDT
Diversion of HIV-1 vaccine-induced immunity by gp41-intestinal microbiota cross-reactive antibodies (No permission to publish slides)
12:15 EDT
Gut microbiome perturbation by oral antibiotics leads to vaccine hypo-responsiveness (Slides not yet available)
Session 5: Vaccines & Therapeutics -
Chairs
Satya Dandekar, PhD
University of California, Davis, USA
Nichole Klatt, PhD
University of Washington, USA
14:00 EDT
Microbial therapeutics and opportunities in HIV
14:30 EDT
Development of a live biotherapeutic product: Opportunities and challenges
15:00 EDT
Abstract Presentation Slot
Rational donor fecal microbiota transplantation in HIV (REFRESH Study) (No permission to publish slides)
Sergio Serrano-Villar
Oral fecal microbiota transplantation increases gut microbiome diversity and alters the microbiome distribution in people with HIV
Netanya Utay
Closing session - 15:45
15:45 EDT
Panel discussion: The Microbiome in HIV Infection - Where do we go from here?
Moderator: Rick Bushman
University of Pennsylvania
Overview
Welcome
We are pleased to look back on a very successful 5th International Workshop on Microbiome in HIV Pathogenesis, Prevention and Treatment, held on the 16th and 17th October 2019 in Rockville, Maryland, USA.
The Organizing Committee and organizers would like to thank the speakers, chairs and all participants for their contribution to this meeting! Special thanks to the workshop support: National Institutes of Health, and sponsors: ViiV Healthcare, Gilead Sciences, Merck, and Metabolon. Without their contribution this workshop would not have been made possible.
Chairs 2019
General Information
Unique Features
The meeting features for the workshop are to its multidisciplinary nature and significance in enabling to learn how the host microbiome can influence responses to our current HIV therapies, and to further our ability to develop novel prevention and therapeutic strategies for HIV that will lead to the reduction of new HIV infections and the burden of non-communicable diseases in HIV infected subjects.
Meeting Objectives
This meeting aims to:
- To gather cross-disciplinary professionals in the field of microbiome research to provide a better understanding of the impact of microbiome changes on HIV outcomes
- To develop a better understanding of how the microbiome effects the pathogenesis of HIV across mucosal sites
- To enhance our knowledge of how the microbiome can impact vaccine responses
- To better understand how the microbiome can contribute to the development of non-communicable diseases
- To use our knowledge of the microbiome field in developing novel strategies for developing microbicides for HIV prevention
- To bring together scientists from across the globe to enhance our understanding of how we can use approaches to modulate the microbiome to reduce levels of inflammation
- To bring together bioinformatics experts in enhancing our ability to analyze complex data generated by sequencing the host microbiome
- To gather cross-disciplinary professionals in the field of microbiome research to provide a better understanding of the impact of microbiome changes on HIV outcomes
- To develop a better understanding of how the microbiome effects the pathogenesis of HIV across mucosal sites
- To enhance our knowledge of how the microbiome can impact vaccine responses
- To better understand how the microbiome can contribute to the development of non-communicable diseases
- To use our knowledge of the microbiome field in developing novel strategies for developing microbicides for HIV prevention
- To bring together scientists from across the globe to enhance our understanding of how we can use approaches to modulate the microbiome to reduce levels of inflammation
- To bring together bioinformatics experts in enhancing our ability to analyze complex data generated by sequencing the host microbiome
Learning Objectives
After participating in this activity, participants will be able to:
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Practical Information
Certificate of Attendance
A digital certificate of attendance was sent to participants upon request by email.
Language
The official language of the workshop was English.
Disclaimer
This workshop is intended for educational purposes only and aims to offer participants the opportunity to share information. The Organizing Secretariat of this workshop, Virology Education, cannot accept any liability for the scientific content of the sessions or for any claims which may result from the use of information or publications from this workshop. Virology Education disclaims all liability for injuries or losses of whatever nature incurred by individuals attending the workshop.
Liability and Insurance
By registering for the conference participants agree that the organizers do not accept responsibility for medical-, travel- or personal insurance. Participants are advised to take out their own insurance policies.
Video recording
Workshop presentations will be posted on this website as soon as possible after the meeting is finished, provided that the speaker has given permission to do so.
Committees
Chairs
Grace Aldrovandi
MD, CM
Ronald G. Collman
MD
Alan Landay
PhD
Organizing Committee
Jason Brenchley
MA, PhD
Rick Bushman
PhD
Satya Dandekar
PhD
Nichole Klatt
PhD
Catherine Lozupone
PhD
Roger Paredes
MD, PhD
Sergio Serrano Villar
MD, PhD
Gilda Tachedjian
BSc (Hons), PhD
Jim A.Turpin
PhD
Laurel Lagenaur
PhD
The members of the Organizing Committee (OC) discuss, on a frequent basis, the scientific program of the workshop, identify interesting topics and candidate speakers.
Scientific Committee
Shaun Barnabas,MD
University of Cape Town, South Africa
Stacy Carrington-Lawrence, PhD
NIH/OAR, USA
Que Dang, PhD
NIAID/NIH, USA
Wendy Henderson, PhD, MSN, CRNP, FAAN
NINR, NIH, DHHS, USA
Steve Innes, MBChB, MRCPCH, MPhil, PhD
Stellenbosch University, South Africa
Douglas Kwon, MD, PhD
Ragon Institute of MGH, MIT and Harvard, USA
Angela Malaspina, PhD
NIAID/NIH, USA
John McGowan, PhD
NIAID, USA
Sandra Pinto Cardoso, PhD
Centre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico
Angela Wahl, PhD
University of North Carolina at Chapel Hill, USA
Cara Wilson, MD
University of Colorado, USA
The members of the Scientific Committee assist the Organizing Committee by providing them with suggestions for speakers and topics. In addition, members of the Scientific Committee participate in reviewing submitted abstracts, and play an active role during the workshop as moderators and/or chairs of sessions.
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