HIVMicrobiome
Meeting category
Date(s)
7 Oct 2020 - 8 Oct 2020
Organizer
Platinum Level Support
Sponsor logos
ViiW

International Workshop on Microbiome in HIV Pathogenesis, Prevention and Treatment 2020

Related Enduring Materials

Enduring Materials

 Day 1 - Wednesday, 7 October 2020

Opening session - 10:00
10:00 EDT
Opening words
Grace Aldrovandi
Grace Aldrovandi, MD, CM
University of California, Los Angeles, USA
Ronald Collman
Ronald Collman, MD
University of Pennsylvania's Perelman School of Medicine, USA
Alan Landay
Alan Landay, PhD
Rush University Medical Center, USA
10:05 EDT
Keynote: Capturing the Dynamics of Phage-bacteria Interactions in the Respiratory Tract Using Metagenomics and Metatranscriptomics
Elodie Ghedin,PhD
Laboratory of Parasitic Diseases of NIAID; NIH, United States
Session 1: Transmission -
Chair
Catherine Lozupone
Catherine Lozupone
University of Colorado Anschutz Medical Campus
Sergio Serrano Villar
Sergio Serrano-Villar, MD, PhD
University Hospital Ramón y Cajal, Madrid, Spain
10:45 EDT
The Impact of Hormonal Contraception on the Vaginal Microbiome and HIV Acquisition
Adam Burgener, PhD
Case Western Reserve University, United States
11:05 EDT
Understanding the Rectal Mucosal Immune Environment and Potential Impacts on HIV Transmission
Colleen Kelley, MD, MPH
Emory University School of Medicine, United States
11:25 EDT
The Microbiome and SIV Acquisition
Jason Brenchley, MA, PhD
National Institutes of Health, United States
Session 2: Pathogenesis -
Chairs
Nichole Klatt
Nichole Klatt, PhD
University of Washington, USA
Jason Brenchley
Jason Brenchley, MA, PhD
National Institutes of Health, USA
12:10 EDT
Intestinal microbial communities and the intestinal microbe Holdemanella biformis isolated from HIV+/- men who have sex with men increase CCR5 expression on intestinal CD4 T cells
Eiko Yamada
#O_01
12:17 EDT
Fecal Proteobacteria Positively Correlates with The Activation of Circulating ISGs and CD4+ T Cells in Vesatolimod-treated HIV Controllers on ART
Yanhui Cai
#O_02
12:24 EDT
Alterations in the Gut Microbiome of HIV infected patients under Antiretroviral Therapy
Shilpa Ray
#O_03
12:31 EDT
Changes in Gut Microbiome in HIV-Infected Individuals Undergoing Long Term Antiretroviral Therapy Receiving Rifaximin: Results of the GUTCHEK Study
James Virga
#O_04
12:45 EDT
Poster viewing 1 (#P_01-P_07)

DAY 2 - Thursday, 8 October 

- 10:00
10:00 EDT
Opening words
Ronald Collman
Chairs: Ronald Collman, MD
University of Pennsylvania's Perelman School of Medicine, USA
Alan Landay
Chairs: Alan Landay, PhD
Rush University Medical Center, USA
10:00 EDT
Keynote: Probing the Microbiome in Disease: From CRC to HIV
Cynthia Sears, MD
Johns Hopkins University, United States
Session 3: Prevention -
Chairs
Gilda Tachedjian
Gilda Tachedjian, BSc (Hons), PhD
Burnet Institute, Melbourne, Australia
Jim A. Turpin
Jim Turpin
NIH, USA
10:40 EDT
Connecting the Dots: Translating the Vaginal Microbiome into a Drug
Laurel Lagenaur, PhD
NIH, Osel, United States
11:00 EDT
Impact of Penile Microbiome on Local Immunology and HIV Susceptibility
Rupert Kaul, PhD, MD, FRCPC
University of Toronto, Canada
11:20 EDT
HIV Replication, Transmission, and the Metabolome of the Female Reproductive Tract
Kaitlin Marquis
#O_05
11:27 EDT
Lactic acid produced by an optimal vaginal microbiota promotes cervicovaginal epithelial barrier integrity: implications for HIV transmission
Brianna Jesaveluk
#O_06
11:50 EDT
Poster viewing 2 (#P_01-P_07)
Session 4: Comorbidities -
Chairs
Roger Paredes
Roger Paredes, MD, PhD
IrsiCaixa AIDS Research Institute, Badalona, Catalonia, Spain
Laurel Lagenaur
Laurel Lagenaur, PhD
NIH, USA
12:20 EDT
Intestinal Cytotoxic CD4+ T Cells are Linked to Immune Activation and Dysbiosis in Untreated HIV infection
Cara Wilson, MD
University of Colorado, United States
12:40 EDT
Microbiome and Cardiometabolic risk in HIV and non-HIV Populations
Marius Trøseid, MD, PhD
University of Oslo, Norway
Session 5: Vaccines & Therapeutics -
Chairs
Rick Bushman
Frederic Bushman
University of Pennsylvania, USA
Satya Dandekar
Satya Dandekar, PhD
University of California, Davis, USA
13:25 EDT
The Microbiome in HIV Vaccines
Roger Paredes, MD, PhD
Hospital Germans Trias & IrsiCaixa AIDS Research Institute, Spain
13:45 EDT
The Impact of the Microbiome on Immunity to Vaccination in Humans
Bali Pulendran, MD, PhD
Stanford University, United States
14:05 EDT
Baseline gut-associated microbial signatures may help predict HIV-1 viral control after treatment interruption
Alessandra Borgognone
O_#07
14:12 EDT
Gut microbial regulation of anxiety disorder in a murine model of HIV-1 and opioid abuse
Shamsudheen Moidunny
#O_08
Closing remarks - 14:30
14:30 EDT
Closing remarks
Grace Aldrovandi
Grace Aldrovandi, MD, CM
University of California, Los Angeles, USA
Ronald Collman
Ronald Collman, MD
University of Pennsylvania's Perelman School of Medicine, USA
Alan Landay
Alan Landay, PhD
Rush University Medical Center, USA
Overview
What's New
Welcome

The 6th International Workshop on Microbiome in HIV Pathogenesis, Prevention and Treatment took place on the 7th and 8th October 2020. 

The understanding of the human microbiome continues to grow rapidly. However information on the role of the microbiome on HIV infection pathogenesis, prevention, and treatment is still limited. Whereas research in this area may be presented at major conferences, there are often limited sessions devoted to this topic as well as limited time for in-depth discussion and debate among cross-disciplinary experts on new data and their implications. The aim of this workshop is to provide increased opportunities for discussion and exchange of knowledge following formal presentation of the latest research.

The multidisciplinary nature and the significance in furthering our ability to develop novel prevention and therapeutic strategies for HIV will lead to the reduction of new HIV infections and the burden of non-communicable diseases in individuals living with HIV. We also will be able to learn how the host microbiome can influence responses to our current HIV therapies.

This 2-day workshop had invited lectures by key opinion leaders, oral abstract presentations, and poster presentations. Ample time was allocated for discussion in an intimate workshop setting. The workshop was unique in its approach, as it engaged basic scientists and clinicians from the HIV field and leading scientists involved in microbiome research including bioinformatics experts.

Clinicians and researchers with an interest in Microbiome in HIV Pathogenesis, Prevention and Treatment were invited to attend this workshop.

Chairs 2020

General Information 

COVID-19 Update
The International Workshop on Microbiome in HIV Pathogenesis, Prevention, and Treatment 2020 was held as a virtual program.

The virtual edition provided an immersive experience to all participants through an interactive platform for real-time Q&A sessions and round-tables to fuel inspiring discussions that will move the microbiome and HIV interaction field forward.

We are available to answer any questions or concerns that you may have about your participation at this new format of the Workshop on Microbiome in HIV 2020. For more information, please contact Federica.Ressa@amededu.com

To stay updated on developments in relation to the Workshop on Microbiome, make sure you are signed up for our newsletter.
Unique Features
The unique features for the workshop include its multidisciplinary nature and significance in enabling participants to learn how the host microbiome can influence responses to our current HIV therapies and to further our ability to develop novel prevention and therapeutic strategies for HIV that will lead to the reduction of new HIV infections and the burden of non-communicable diseases in individuals living with HIV.
Meeting Objectives
This meeting aims to:

- To gather cross-disciplinary professionals in the field of microbiome research to provide a better understanding of the impact of microbiome changes on HIV outcomes

- To develop a better understanding of how the microbiome effects the pathogenesis of HIV across mucosal sites

- To enhance our knowledge of how the microbiome can impact vaccine responses

- To better understand how the microbiome can contribute to the development of non-communicable diseases

- To use our knowledge of the microbiome field in developing novel strategies for developing microbicides for HIV prevention

- To bring together scientists from across the globe to enhance our understanding of how we can use approaches to modulate the microbiome to reduce levels of inflammation

- To bring together bioinformatics experts in enhancing our ability to analyze complex data generated by sequencing the host microbiome
Learning Objectives
After participating in this activity, participants will be able to:

- To recall the complex interplay between the human microbiome, host immunity, and pathogenesis

- To translate research achievements into challenges for the development of preventive approaches to reduce virus transmission

Practical Information 

Certificate of Attendance
A digital certificate of attendance was sent to participants upon request by email.
Language
The official language of the workshop was English.
No simultaneous translation was provided.
Disclaimer
This workshop is intended for educational purposes only and aims to offer participants the opportunity to share information. The Organizing Secretariat of this workshop, Virology Education, cannot accept any liability for the scientific content of the sessions or for any claims which may result from the use of information or publications from this workshop. Virology Education disclaims all liability for injuries or losses of whatever nature incurred by individuals attending the workshop.
Liability and Insurance
By registering for the conference participants agree that the organizers do not accept responsibility for medical-, travel- or personal insurance. Participants are advised to take out their own insurance policies.
Video Recordings
All presentations that we were granted permission for will be posted on the workshop website as soon as possible after the workshop is finished, provided that the speaker has given permission to do so.
Committees
Chairs 2020
Organizing Committee

The members of the Organizing Committee (OC) discuss, on a frequent basis, the scientific program of the workshop, identify interesting topics and candidate speakers.

Scientific Committee

The members of the Scientific Committee assist the Organizing Committee by providing them with suggestions for speakers and topics. In addition, members of the Scientific Committee participate in reviewing submitted abstracts, and play an active role during the workshop as moderators and/or chairs of sessions.

  • Shaun Barnabas, MD - University of Cape Town, South Africa

  • Stacy Carrington-Lawrence, PhD - NIH/OAR, USA

  • Que Dang, PhD - NIAID/NIH, USA

  • Wendy Henderson, PhD, MSN, CRNP, FAAN - NINR, NIH, DHHS, USA

  • Steve Innes, MBChB, MRCPCH, MPhil, PhD - Stellenbosch University, South Africa

  • Douglas Kwon, MD, PhD - Ragon Institute of MGH, MIT and Harvard, USA

  • Angela Malaspina, PhD - NIAID/NIH, USA

  • John McGowan, PhD - NIAID, USA

  • Piotr Nowak, MD, PhD - Karolinska University Hospital, Sweden

  • Sandra Pinto Cardoso, PhD - Centre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico

  • Angela Wahl, PhD - University of North Carolina at Chapel Hill, USA

  • Cara Wilson, MD - University of Colorado, USA

Support

In order to deliver this event, we depend on corporate support. Collaboration with the pharmaceutical industry is vital for both the organizational as well as the scientific success of the program.

For industry support opportunities please contact our managing director Mrs. Alice Posthumus-Plantinga at alice.posthumus-plantinga@amededu.com or call +31 6 2248 2179. 

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